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Short-term effects of excessive anaerobic reaction time on anaerobic metabolism of denitrifying polyphosphate- accumulating organisms linked to phosphorus removal and N

Gang GUO, Yayi WANG, Chong WANG, Hong WANG, Mianli PAN, Shaowei CHEN

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 4,   Pages 616-624 doi: 10.1007/s11783-013-0505-4

Abstract: The fluorescence in situ hybridization (FISH) analysis revealed that the sludge was mainly dominated

Keywords： Denitrifying phosphorus removal     anaerobic reaction time     nitrous oxide     polyhydroxyalkanoate     free nitrous acid     fluorescencein-situ hybridization    

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Potential unreliability of ALK variant allele frequency in the efficacy prediction of targeted therapy in NSCLC

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 493-502 doi: 10.1007/s11684-022-0946-x

Abstract: Anaplastic lymphoma kinase (ALK) is the most common fusion gene involved in non-small cell lung cancer (NSCLC), and remarkable response has been achieved with the use of ALK tyrosine kinase inhibitors (ALK-TKIs). However, the clinical efficacy is highly variable. Pre-existing intratumoral heterogeneity (ITH) has been proven to contribute to the poor treatment response and the resistance to targeted therapies. In this work, we investigated whether the variant allele frequencies (VAFs) of ALK fusions can help assess ITH and predict targeted therapy efficacy. Through the application of next-generation sequencing (NGS), 7.2% (326/4548) of patients were detected to be ALK positive. On the basis of the adjusted VAF (adjVAF, VAF normalization for tumor purity) of four different threshold values (adjVAF < 50%, 40%, 30%, or 20%), the association of ALK subclonality with crizotinib efficacy was assessed. Nonetheless, no statistical association was observed between median progression-free survival (PFS) and ALK subclonality assessed by adjVAF, and a poor correlation of adjVAF with PFS was found among the 85 patients who received first-line crizotinib. Results suggest that the ALK VAF determined by hybrid capture-based NGS is probably unreliable for ITH assessment and targeted therapy efficacy prediction in NSCLC.

Keywords： ALK fusion     next-generation sequencing     fluorescence in situ hybridization     immunohistochemistry    

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Polyolefin-nanocomposites with special properties by in-situ polymerization

Walter Kaminsky

Frontiers of Chemical Science and Engineering 2018, Volume 12, Issue 3,   Pages 555-563 doi: 10.1007/s11705-018-1715-x

Abstract:

Exceptionally strong polyolefin nanocomposites are synthesized by in-situ polymerization using

Keywords： polyolefin nanocomposites     metallocenes     methylaluminoxane    

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Development of an H reduction and moderate oxidation method for 3,5-dimethylpyridine hydrogenation in trickle bed reactor

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 12,   Pages 1807-1817 doi: 10.1007/s11705-022-2243-2

Abstract: Under the same reduction conditions (300 °C in H2), the catalytic activity of the non-in-situ reduced Ru/C-n catalyst was higher than that of the in-situ reduced Ru/C-y catalyst.Therefore, an in-situ H2 reduction and moderate oxidation method was developed to increaseThe developed in-situ H2 reduction and moderate oxidation method eliminated the stepof the non-in-situ reduction of catalyst outside the trickle bed reactor.

Keywords： Ru/C catalyst     in-situ H2 reduction and moderate oxidation     in-situ reduction     non-in-situ reduction     hydrogenation of 3     5-dimethylpyridine    

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Niche Differentiation of Phenol-Degrading Microorganisms in UASB Granular Sludge as Revealed by Fluorescencein situ Hybridization Article

Kengo Kubota, Kei Igarashi, Masayoshi Yamada, Yasuyuki Takemura, Yu-You Li, Hideki Harada

Engineering 2022, Volume 9, Issue 2,   Pages 61-66 doi: 10.1016/j.eng.2021.05.012

Abstract: harvested from an anaerobic sludge blanket reactor treating phenolic wastewater was investigated using fluorescencein situ hybridization (FISH) and clone library construction.

Keywords： Cryptanaerobacter     Fluorescence     in situ     hybridization     Anaerobic phenol degradation     Syntrophorhabdaceae    

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hydrophobic environment triggering reactive fluorescence probe to real-time monitor mitochondrial DNA

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 92-102 doi: 10.1007/s11705-021-2063-9

Abstract: Herein, we constructed an in situ hydrophobic environment-triggering reactive fluorescence probeThus, MBI-CN can be hydrolyzed to generate MBI-CHO in an in situ hydrophobic environment withMeanwhile, MBI-CHO immediately emitted a significative fluorescence signal changes at 437 and 553 nm

Keywords： hydrolysis reaction     mitochondrial DNA damage     in situ hydrophobic environment trigger     fluorescence    

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In-situ condition monitoring of reinforced concrete structures

Sanjeev Kumar VERMA,Sudhir Singh BHADAURIA,Saleem AKHTAR

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 4,   Pages 420-437 doi: 10.1007/s11709-016-0336-z

Abstract: deterioration mechanisms, performance characteristics and parameters and condition monitoring of in situ

Keywords： concrete     carbonation     chloride     corrosion     monitoring     models    

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Organics Recovery from Waste Activated Sludge In-situ Driving Efficient Nitrogen Removal from Mature

Fangzhai Zhang,Shang Ren,Haoran Liang,Zhaozhi Wang,Ying Yan,Jiahui Wang,Yongzhen Peng,

Engineering doi: 10.1016/j.eng.2023.03.005

Abstract: free nitrous acid (FNA) to realize sustainable organics recovery from waste activated sludge (WAS) in-situ

Keywords： Waste activated sludge     Bioresource recovery     Simultaneous treatment of wastewater and sludge     Mature landfill leachate     Free nitrous acid    

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Thermodynamic analysis of liquid phase in situ hydrogenation of glycerol for 1,3-propanediol synthesis

Kun OUYANG, Yu HUANG, Haoyi CHEN, Tao LI, Fahai CAO, Dingye FANG

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 1,   Pages 67-73 doi: 10.1007/s11705-010-0541-6

Abstract: reforming (APR) and catalytic hydrogenation of glycerol, a novel reaction system of liquid phase in situreforming reaction; the hydrogen generated from the APR of glycerol can be quickly transformed to the in situ

Keywords： glycerol     aqueous-phase reforming     1     3-propanediol     in-situ reduction    

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density measurement for plastic injection molding via ultrasonic technology

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 4, doi: 10.1007/s11465-022-0714-2

Abstract: Therefore, in-situ density measurement is of great interest and has significant application valueThis study is the first to propose an in-situ density measurement method using ultrasonic technologyThe proposed method has the advantages of in-situ measurement, non-destructive, high accuracy,

Keywords： ultrasonic measurement     melt density     in-situ measurement     injection molding    

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A novel six-legged walking machine tool for

Jimu LIU, Yuan TIAN, Feng GAO

Frontiers of Mechanical Engineering 2020, Volume 15, Issue 3,   Pages 351-364 doi: 10.1007/s11465-020-0594-2

Abstract: The manufacture and maintenance of large parts in ships, trains, aircrafts, and so on create an increasing demand for mobile machine tools to perform operations. However, few mobile robots can accommodate the complex environment of industrial plants while performing machining tasks. This study proposes a novel six-legged walking machine tool consisting of a legged mobile robot and a portable parallel kinematic machine tool. The kinematic model of the entire system is presented, and the workspace of different components, including a leg, the body, and the head, is analyzed. A hierarchical motion planning scheme is proposed to take advantage of the large workspace of the legged mobile platform and the high precision of the parallel machine tool. The repeatability of the head motion, body motion, and walking distance is evaluated through experiments, which is 0.11, 1.0, and 3.4 mm, respectively. Finally, an application scenario is shown in which the walking machine tool steps successfully over a 250 mm-high obstacle and drills a hole in an aluminum plate. The experiments prove the rationality of the hierarchical motion planning scheme and demonstrate the extensive potential of the walking machine tool for operations on large parts.

Keywords： legged robot     parallel mechanism     mobile machine tool     in-situ machining    

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Comprehensive kinetostatic modeling and morphology characterization of cable-driven continuum robots for aero-engine maintenance

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 3, doi: 10.1007/s11465-023-0756-0

Abstract: In-situ maintenance is of great significance for improving the efficiency and ensuring the safetyemerged as a novel tool that aims to promote the development of intelligence and efficiency for in-situkinematic and morphology of CDCR lays the foundation for the accurate operation and control for in-situsystem is integrated to experimentally validate the proposed kinetostatic model and the concept of in-situThe compact continuum robot system could be considered a novel solution to perform in-situ maintenance

Keywords： kinetostatic modeling     morphology characterization     variable friction     continuum robots     in-situ   

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grown TiN/N-TiO composite for enhanced photocatalytic H evolution activity

Frontiers in Energy 2021, Volume 15, Issue 3,   Pages 721-731 doi: 10.1007/s11708-021-0766-8

Abstract: decorated N-doped titania (N-TiO2) composite (TiN/N-TiO2) is fabricated via an in situThe results indicate that the superior activity is mainly caused by the in situ formationThe present study provides a fascinating approach to in situ forming nonmetallic plasmonic material

Keywords： photocatalytic H2 evolution     TiN/N-TiO2 composite     plasmonic effect     in-situ    

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Carbon-coated Ni-Co alloy catalysts: preparation and performance for aqueous phase hydrodeoxygenation of methyl palmitate to hydrocarbons using methanol as the hydrogen donor

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 3,   Pages 443-460 doi: 10.1007/s11705-021-2079-1

Abstract: In the in-situ aqueous phase hydrodeoxygenation of methyl palmitate with methanol as the hydrogen

Keywords： Stöber method     carbon-coated Ni-Co alloy     in-situ hydrodeoxygenation     methyl palmitate     decarbonylation    

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Room temperature preparation of hydrazine-linked covalent organic frameworks coated capillaries for separation and determination of polycyclic aromatic hydrocarbons

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 5,   Pages 548-556 doi: 10.1007/s11705-022-2252-1

Abstract: The TFPB-DHzDS coated capillaries were prepared by an in-situ growth process at room temperature

Keywords： hydrazine-linked TFPB-DHzDS     in-situ growth method     open-tubular capillary electrochromatography    

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Title Author Date Type Operation

Short-term effects of excessive anaerobic reaction time on anaerobic metabolism of denitrifying polyphosphate- accumulating organisms linked to phosphorus removal and N

Gang GUO, Yayi WANG, Chong WANG, Hong WANG, Mianli PAN, Shaowei CHEN

Journal Article

Potential unreliability of ALK variant allele frequency in the efficacy prediction of targeted therapy in NSCLC

Journal Article

Polyolefin-nanocomposites with special properties by in-situ polymerization

Walter Kaminsky

Journal Article

Development of an H reduction and moderate oxidation method for 3,5-dimethylpyridine hydrogenation in trickle bed reactor

Journal Article

Niche Differentiation of Phenol-Degrading Microorganisms in UASB Granular Sludge as Revealed by Fluorescencein situ Hybridization

Kengo Kubota, Kei Igarashi, Masayoshi Yamada, Yasuyuki Takemura, Yu-You Li, Hideki Harada

Journal Article

hydrophobic environment triggering reactive fluorescence probe to real-time monitor mitochondrial DNA

Journal Article

In-situ condition monitoring of reinforced concrete structures

Sanjeev Kumar VERMA,Sudhir Singh BHADAURIA,Saleem AKHTAR

Journal Article

Organics Recovery from Waste Activated Sludge In-situ Driving Efficient Nitrogen Removal from Mature

Fangzhai Zhang,Shang Ren,Haoran Liang,Zhaozhi Wang,Ying Yan,Jiahui Wang,Yongzhen Peng,

Journal Article

Thermodynamic analysis of liquid phase in situ hydrogenation of glycerol for 1,3-propanediol synthesis

Kun OUYANG, Yu HUANG, Haoyi CHEN, Tao LI, Fahai CAO, Dingye FANG

Journal Article

density measurement for plastic injection molding via ultrasonic technology

Journal Article

A novel six-legged walking machine tool for

Jimu LIU, Yuan TIAN, Feng GAO

Journal Article

Comprehensive kinetostatic modeling and morphology characterization of cable-driven continuum robots for aero-engine maintenance

Journal Article

grown TiN/N-TiO composite for enhanced photocatalytic H evolution activity

Journal Article

Carbon-coated Ni-Co alloy catalysts: preparation and performance for aqueous phase hydrodeoxygenation of methyl palmitate to hydrocarbons using methanol as the hydrogen donor

Journal Article

Room temperature preparation of hydrazine-linked covalent organic frameworks coated capillaries for separation and determination of polycyclic aromatic hydrocarbons

Journal Article